Nanobiology, a relatively new field of science, is a field that studies life at the nanoscale. To do so, it integrates knowledge from exact sciences and biology. As a student of Nanobiology and Philosophy I wonder whether this integration is actually possible. In my search for answers I am inspired by “Making Sense of Life” (2002) by Evelyn Fox Keller, a work that illustrates the diversity in explanations of the development of living organisms and the fundamental divide between exact sciences and biology concerning explanatory styles. In this thesis I argue, based on examples from Keller and own experience, that explanatory styles from physics and biology, although fundamentally different, can empower each other to gain better insight in what life is all about.